ÎåÐÇÌåÓýÖ±²¥

Form: SC 13G/A

Schedule filed to report acquisition of beneficial ownership of 5% or more of a class of equity securities by passive investors and certain institutions

February 10, 2016

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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SCHEDULE 13G

(Rule 13d-102)

INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT

TO §240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO §240.13d-2

Amendment No. 1

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CODEXIS, INC.

(Name of Issuer)

COMMON STOCK, $0.0001 PAR VALUE

(Title of Class of Securities)

192005106

(CUSIP Number)

DECEMBER 31, 2015

(Date of Event Which Requires Filing of This Statement)

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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

¨ Rule 13d-1(b)

¨ Rule 13d-1(c)

x Rule 13d-1(d)

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* The remainder of this cover page shall be filled out for a reporting personÂ’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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Presidio Partners 2014, L.P.

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýDelaware

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýPN

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CUSIPÌýNo. 192005106 Ìý Page 3 of 10 Pages

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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Presidio Partners 2014 GP, LLC

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýDelaware

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýPN

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CUSIPÌýNo. 192005106 Ìý Page 4 of 10 Pages

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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Peter Gajdos

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýSlovak Republic

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýIN

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CUSIPÌýNo. 192005106 Ìý Page 5 of 10 Pages

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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David J. Collier

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýUnited States of America

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýIN

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CUSIPÌýNo. 192005106 Ìý Page 6 of 10 Pages

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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Faysal A. Sohail

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýUnited States of America

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýIN

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CUSIPÌýNo. 192005106 Ìý Page 7 of 10 Pages

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ÌýÌý1.Ìý Ìý

Name of Reporting Persons

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James F. Watson

ÌýÌý2. Ìý

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)ÌýÌý¨ÌýÌýÌýÌýÌýÌýÌýÌý(b)ÌýÌý¨

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ÌýÌý3. Ìý

SEC USE ONLY

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ÌýÌý4. Ìý

Citizenship or Place of Organization

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ÌýÌýÌýÌýUnited States of America

NumberÌýof

Shares

Beneficially

OwnedÌýby

Each

Reporting

Person

With:

ÌýÌý 5.Ìý ÌýÌý

Sole Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 6. ÌýÌý

Shared Voting Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 7. ÌýÌý

Sole Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý 8. ÌýÌý

Shared Dispositive Power

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ÌýÌýÌýÌýSee Item 5

ÌýÌý9. Ìý

Aggregate Amount Beneficially Owned by Each Reporting Person

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ÌýÌýÌýÌýSee Item 5

10. Ìý

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)ÌýÌýÌýÌý¨

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11. Ìý

Percent of Class Represented by Amount in Row (9)

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ÌýÌýÌýÌýSee Item 5

12. Ìý

Type of Reporting Person (See Instructions)

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ÌýÌýÌýÌýIN

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CUSIP No. 192005106 ÌýÌý Page 8 of 10 Pages

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ItemÌý1(a) Name of Issuer

ÎåÐÇÌåÓýÖ±²¥ (the “Issuer”).

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ItemÌý1(b) Address of IssuerÂ’s Principal Executive Offices

200 Penobscot Drive, Redwood City, California 94063

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ItemÌý2(a) Name of Person Filing

Presidio Partners 2014, L.P. (“Presidio LP”); Presidio Partners 2014 GP, LLC (“Presidio GP”), which is the sole General Partner of Presidio LP; Peter Gajdos (“Gajdos”), David J. Collier (“Collier”), Faysal A. Sohail (“Sohail”), and James F. Watson (“Watson”), each of whom is a Manager of Presidio GP. Presidio LP, Presidio GP, Gajdos, Collier, Sohail and Watson are referred to individually herein as “Reporting Person” and collectively as the “Reporting Persons.”

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ItemÌý2(b) Address of Principal Business Office or, if none, Residence

The address of the principal business office of each of the Reporting Persons is c/o Presidio Partners 2014, L.P., 1 Letterman Drive, Building C, Suite CM 500, San Francisco, CA 94129.

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ItemÌý2(c) Citizenship

Presidio LP is a limited partnership organized under the laws of the State of Delaware. Presidio GP is a limited liability company organized under the laws of the State of Delaware. Each of Collier, Sohail and Watson is a United States citizen. Gajdos is a citizen of the Slovak Republic.

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ItemÌý2(d) Title of Class of Securities

Common Stock, $0.0001 par value

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ItemÌý2(e) CUSIP Number

192005106

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ItemÌý3 If this Statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.

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ItemÌý4 Ownership

(a) Amount beneficially owned: See ItemÌý5

(b) Percent of Class: See Item 5

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(c) Ìý Number of shares as to which such person has: Ìý
Ìý (i) Ìý sole power to vote or to direct the vote: Ìý SeeÌýItemÌý5
Ìý (ii) Ìý shared power to vote or to direct the vote: Ìý SeeÌýItem 5
Ìý (iii) Ìý sole power to dispose or to direct the disposition of: Ìý SeeÌýItem 5
Ìý (iv) Ìý shared power to dispose or to direct the disposition of: Ìý SeeÌýItem 5

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ItemÌý5 Ownership of Five Percent or Less of a Class.

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following x.

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ItemÌý6 Ownership of More than Five Percent of Another Person.

Not applicable.


CUSIP No. 192005106 ÌýÌý Page 9 of 10 Pages

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ItemÌý7 Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company.

Not applicable.

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ItemÌý8 Identification and Classification of Members of the Group

Not applicable. The Reporting Persons expressly disclaim membership in a “group” as used in Rule 13d-5(b).

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ItemÌý9 Notice of Dissolution of Group

Not applicable.

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ItemÌý10 Certification

By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.


SIGNATURE

After reasonable inquiry and to the best of its knowledge and belief, each of the undersigned certified that the information set forth in this statement is true, complete and correct.

EXECUTED this 10th day of February, 2016.

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PRESIDIO PARTNERS 2014, L.P.
By: Ìý

/s/ James F. Watson

Ìý Name: Ìý James F. Watson
Ìý Title: Ìý Manager
Presidio Partners 2014 GP, LLC
By: Ìý

/s/ James F. Watson

Ìý Name: Ìý James F. Watson
Ìý Title: Ìý Manager
By: Ìý

/s/ Peter Gajdos

Peter Gajdos
By: Ìý

/s/ David J. Collier

David J. Collier
By: Ìý

/s/ Faysal A. Sohail

Faysal A. Sohail
By: Ìý

/s/ James F. Watson

James F. Watson