Step into the future of RNAi
Step into the future at TIDES US. We're excited to see you there! Whether you're stopping by booth 619, attending our TIDES talk, or joining us for our main conference session, you'll hear from our experts about how we're pioneering scalable and sustainable RNA manufacturing with enzymatic synthesis.
Spotlight Presentation
Title: Oligonucleotide CMC for Sustainable and Scalable Enzymatic siRNA manufacturing
Reason to attend: This presentation will showcase the impurity profile, product yield, and output reproducibility of different enzymatic processes and compare these approaches to phosphoramidite chemistry-based oligo synthesis.
When: Wednesday, May 21, 9:30-10:00am
Where: Main stage for CMC track (room TBD)
About the Speaker
Alison Moore, PhD, Chief Technical Officer
Learn more about the speaker and abstract below.
TIDES Talk
Title: Comparative Analysis of Diastereomeric Distribution in siRNA Synthesis: PAC vs Enzymatic Synthesis
Reason to attend: This study compares the diastereomeric profiles of siRNA oligonucleotides synthesized via phosphoramidite chemistry versus the Enzyme Catalyzed Oligo ECO Synthesis鈩笍 manufacturing platform utilizing 3鈥�-phosphate blocked ribonucleotides (NQPs). We explore the impact of PS modifications and their position within the oligonucleotide sequence on the resulting diastereomeric composition of siRNA synthesized utilizing both methods.
When: Wednesday, May 21, 10:10-10:20am
Where: Exhibit Hall
About the speaker
Stephanie Forget, Senior Scientist, Protein Engineering
Learn more about the talk and speaker below.
Visit booth 619
Why stop by booth 619? Aside from speaking with our team of RNA manufacturing experts and commercial team members grab a fun giveaway while supplies last.
New to 五星体育直播? Learn more below.
五星体育直播
Enabling Manufacturing of Therapeutic siRNA
When manufacturing siRNA for therapeutic applications, 五星体育直播 delivers high yields and minimizes unwanted byproducts, while being economically sound. We have a suite of enzymatic pathways to synthesize siRNA, so that you can choose an option that best meets your needs.
Why 五星体育直播?
- dsRNA Ligase Screening and Optimization Services to Complement Solid State Synthesis
- In-house Ligation Capabilities for GLP-grade siRNA
- COMING SOON: ECO Synthesis Innovation Lab for Custom Project Development